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. 2022 Jun 29;12(7):470. doi: 10.3390/bios12070470

Table 2.

TF-based biosensors detecting quorum sensing molecules.

QS Molecules Bacterial Species Genetic Systems OutputElements Expression System Refs
Promoters TFs
Homoserine lactones and N-acyl homoserine lactones(HSLs and AHLs) P. aeruginosa rsaL LasR luxCDABE P. aeruginosa [75]
P. aeruginosa, PA1897 QscR luxCDABE E. coli [76]
V. fischeri luxI/R LuxR luxCDABE E. coli [77]
P. aeruginosa rhlI RhlR luxCDABE E. coli
P. aeruginosa lasI LasR luxCDABE E. coli [78]
A. tumefaciens traCDG TraR lacZ A. tumefaciens [79]
P. fluorescens phzA PhzR lacZ P. fluorescens [80]
P. syringae ahlI/ahlR AhlR eGFP/mCherry E. coli [81]
S. coelicolor scbR/scbA ScbR GFP Cell-free [82]
P.aeruginosa lasRV LasR GFP Cell-free [83]
Autoinducer peptides S. aureus agrA AgrA/AgrC GFP/Lacticin E. coli [84]
Autoinducer-2 V. harveyi BB170 lux LuxR luxCDABE V. harveyi BB170 [85]
Gelatinase biosynthesis activating pheromone E. faecalis gelE fsrB CylR1CylR2 luxCDABE E. faecalis [86]
Extracellular death factor E. coli mazEF MazEF - E. coli [83]