Table 5.
Multivariate models (adjusting for age, gender, BMI, and DM), revealing the diagnostic values of targeted urine biomarkers.
| p-Value | Odds Ratio | 95% CI | Odds Ratio Units * | |
|---|---|---|---|---|
| IC/BPS (Total) vs. control | ||||
| MCP-1 | 0.002 | 2.030 | 1.286–3.205 | 100 |
| 8-OHdG | <0.001 | 1.687 | 1.258–2.264 | 10 |
| 8-isoprostane | 0.002 | 1.557 | 1.176–2.060 | 10 |
| Eotaxin | 0.017 | 1.141 | 1.024–1.271 | 1 |
| RANTES | 0.048 | 1.102 | 1.001–1.213 | 1 |
| IC/BPS (ESSIC type 2) vs. control | ||||
| MCP-1 | 0.002 | 2.362 | 1.377–4.050 | 100 |
| 8-OHdG | 0.000 | 2.056 | 1.448–2.919 | 10 |
| 8-isoprostane | 0.003 | 1.512 | 1.152–1.987 | 10 |
| CXCL 10 | 0.030 | 1.224 | 1.020–1.468 | 10 |
| Eotaxin | 0.014 | 1.165 | 1.032–1.316 | 1 |
| RANTES | 0.036 | 1.116 | 1.007–1.238 | 1 |
| IC/BPS (ESSIC type 2) vs. IC/BPS (ESSIC type 1) | ||||
| 8-OHDG | 0.001 | 1.456 | 1.161–1.826 | 10 |
*: units: all pg/mL, except ng/mL in 8-OHdG, and mmol/μL in TAC.