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. 2022 Jul 17;10(7):1722. doi: 10.3390/biomedicines10071722

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Risk of VCI according to ART type. Pooled odds ratios (ORs) were calculated using RevMan version 5.4.1 (Cochrane Collaboration, Copenhagen, Denmark). Thus, some values may be slightly different from their original state. The following comparisons were performed to determine VCI risk: (A,B) blastocyst transfer versus cleavage stage transfer (A, unadjusted; B, adjusted), (C) frozen ET versus fresh ET, and (D) frozen ET with versus without PGT. Forest plots were arranged according to the year of publication. Substantial heterogeneity was observed in the analysis of (A,B) (A, I² = 87%; B, I² = 94%), whereas no heterogeneity was observed in analysis of (C) (C, I² = 0%). Abbreviations: VCI, velamentous cord insertion; ART, assisted reproductive technology; blastocyst, blastocyst transfer; cleavage stage transfer; frozen ET, frozen embryo transfer; fresh ET, fresh embryo transfer; PGT, preimplantation genetic testing; OR, odds ratio; CI, confidence interval; SE, standard error.