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Percent change in secondary structure content (∆SSE) from experimentally determined structures to AlphaFold predicted structures. (a) ∆SSE of all loop regions. Greater than 90% of loops have a ∆SSE of 0%. (b) Average ∆SSE as a function of the number of residues in a loop with standard error bars. (c) Average ∆SSE as a function of the number of residues in a loop with linear regression (R2 = 0.4204). ∆SSE increases as the number of residues in the loop regions increases.
