Table 1.
Fraction of DSSP secondary structure types in experimentally determined and AlphaFold 2 predicted structures. AlphaFold 2 predicted secondary structure content (parallel beta sheet, antiparallel beta sheet, alpha helix, pi helix, or 3–10 helix) in 2.28% of loop residues.
| DSSP Secondary Structure Type | Experimental Structures | AlphaFold 2 Structures |
|---|---|---|
| None | 78.64% | 76.66% |
| Turn | 12.92% | 14.51% |
| Bend | 8.44% | 6.55% |
| Parallel beta sheet | 0% * | 0.10% |
| Antiparallel beta sheet | 0% * | 0.16% |
| Alpha helix | 0% * | 0.74% |
| Pi helix | 0% * | 0.03% |
| 3–10 helix | 0% * | 1.25% |
* By definition, the experimental structures of loop regions in our dataset have 0% parallel beta sheet, antiparallel beta sheet, alpha helix, pi helix, and 3–10 helix.