Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jun 24;12(7):881. doi: 10.3390/biom12070881

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Scheme 1 — Synthetic routes for (S)-MK-26 ((1)^a). ^a Reagents and conditions: (a) BF₃•Et₂O, CH₃COOH, r.t. overnight; (b) CH₃COOH, H₂O₂, r.t. overnight; (c) chiral separations, Chiralpack IA column, isocratic 100% EtOAc as mobile phase (d) I. (+)-diisopropyl L-tartrate, titanium (IV) isopropoxide, acetone, H₂O, reflux 1 h, II. DIPEA, cumene hydroperoxide, acetone, r.t. 3 h.