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. 2022 Jul 17;10(7):1723. doi: 10.3390/biomedicines10071723

Table 1.

The Cancer Genome Atlas Program expression data analysis for the correlation between iNKT cells signature and M1- or M2-like macrophages signatures on colon adenocarcinoma and normal adjacent tissue.

Colon Adenocarcinoma Normal Adjacent Tissue
M1 Signature M2 Signature M1 Signature M2 Signature
R p R p R p R p
CD3 0.68 0 0.56 0 0.49 0.0012 0.022 0.89
TRAV10 0.49 0 0.40 2.9 × 10−12 0.52 5.0 × 10−4 0.23 0.16
TRBV25-1 0.67 0 0.54 0 0.49 0.0012 −0.0069 0.97
TRAV10+TRBV25-1 0.79 0 0.63 0 0.57 0.00011 0.064 0.69

M1-like macrophage signature—CD40, HLA-DRA, CD80 and CD86; M2-like macrophage signature—CD163 and CD206; iNKT cell signature—TRAV10 and TRBV25-1.