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. 2022 Jul 2;12(7):930. doi: 10.3390/biom12070930

Figure 1.

Figure 1

‘Bi-directional’ effect of deregulated microRNAs in HCC. MiR-21 and miR-17-92 cluster regulate both HCC phenotype and immune system activation or repression. Their pro- or antitumorigenic effects depend on the regulation of different immune cell subpopulations.