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Summary of the construction of ECL biosensors based on porous nanocomposites for nucleic acids detection.
| Analytes | Nanocomposites | Linear Range | LOD | Ref. |
|---|---|---|---|---|
| miRNA-182 | mSiO2@CdTe@SiO2 NSs | 0.1 to 100 pM | 33 fM | [30] |
| microRNA-21 | Zn-PTC | 100 aM to 100 pM | 29.5 aM | [68] |
| miRNA-133a | Zn-MOF | 50 aM to 50 fM | 35.8 aM | [74] |
| microRNA-21 | Py-sp2c-COF | 100 aM to 1 nM | 46 aM | [97] |
| microRNA-21 | Co-MOF-ABEI/Ti3C2Tx | 0.00001 to 10 nM | 3.7 fM | [98] |
| miRNA-155 | RuMOFs | 0.8 fM to 1.0 nM | 0.3 fM | [99] |
