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. 2022 Jul 12;10(7):1680. doi: 10.3390/biomedicines10071680

Figure 1.

Figure 1

CXCR4 expression in tissue microarrays obtained from endometrial cancer patients. (A) CXCR4 is overexpressed in tumor tissue (n = 79), as compared to adjacent healthy endometrial tissue (n = 27), that shows almost undetectable CXCR4 expression levels by immunohistochemistry (IHC) (Mann–Whitney test, *** p = 0.000; mean ± s.e.m). (B) CXCR4 protein expression after IHC is negligible in healthy endometrial tissue, whereas it is highly overexpressed and mostly located in the cell membrane of tumor endometrial tissue. Bar: 20 µm. NT: non-tumor, healthy tissue; T: tumor tissue.