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. 2022 Jun 24;10(7):1497. doi: 10.3390/biomedicines10071497

Figure 1.

Figure 1

Reduced expression of mitochondria-encoded genes in lung tissue in smokers and emphysema. The expression of mitochondria-encoded (A) and nuclear-encoded (B) mitochondrial genes was determined by RT-PCR in lung tissue obtained from control nonsmokers (NS), smokers (SM), and patients with emphysema (EM). Mitochondrial protein levels were assessed by Western blotting (C), quantified, and normalized to β-actin expression (D). Data are shown as means ± s.e.m (N = 4–10 per group; * p < 0.05; ** p < 0.01).