Table 4.
Light microscopy and electron microscopy findings of the renal biopsy specimens.
| Patient No. |
Sex/Age (yr) | Global Sclerosis |
Segmental Sclerosis |
Glomerular Hyaline | Interstitial Fibrosis | Tubular Atrophy |
Arterio- Pathy |
Podocyte GL3 Deposits | Tubular GL3 Deposits |
Glomerular Endothelial Cell GL3 Deposits |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | M/17 | + | + | − | + | NA | + | + | + | + |
| 2 | M/10 | − | − | − | − | − | − | + | + | + |
| 3 | M/41 | − | − | − | + | NA | + | + | + | + |
| 4 | M/26 | − | − | − | − | − | − | + | + | + |
| 5 | M/44 | − | + | + | + | + | + | + | + | + |
| 6 | M/39 | + | + | + | + | + | − | + | + | + |
| 7 | M/29 | − | + | − | − | − | − | + | + | + |
| 8 | F/50 | + | + | − | + | + | + | + | + | + |
| 9 | F/55 | + | + | + | + | + | + | + | + | + |
| 10 | F/49 | − | − | − | − | + | − | + | + | + |
| 11 | F/46 | − | − | − | − | − | − | + | + | + |
| 12 | F/30 | − | − | − | − | − | − | + | + | + |
| 13 | F/35 | − | − | − | − | − | − | + | + | + |
| 14 | F/63 | − | − | − | − | NA | − | + | + | − |
| 15 | F/35 | + | + | − | − | − | + | + | + | + |
| 16 | F/61 | − | − | − | + | NA | + | + | + | + |
| 17 * | M/43 | − | + | − | + | + | + | + | + | + |
| 18 * | M/32 | − | − | − | − | − | − | + | + | + |
| 19 * | M/58 | − | + | − | + | + | − | + | + | + |
| 20 * | M/37 | + | + | − | + | + | − | + | + | + |
| 21 * | F/57 | − | + | + | − | − | − | + | + | + |
* Previously enzyme replacement therapy-treated patients; Plus (+) sign represents the presence and minus (−) sign represent the absence; M = male, F = female; NA = not applicable; GL3 = globotrioasylceramide.