Table 2.

Organ weight versus body weight coefficients.

Organs/Group		Organs Weights, % of Body Weight
		4 M	6 M	18 M
Brain	WT	1.2 ± 0.02	1.2 ± 0.05	1.3 ± 0.02
	Sig1R KO	1.3 ± 0.03 *	1.3 ± 0.08 *	1.4 ± 0.03 *
Heart	WT	0.5 ± 0.01	0.5 ± 0.03	0.5 ± 0.02
	Sig1R KO	0.4 ± 0.01	0.4 ± 0.01 *	0.4 ± 0.05 *
Kidney	WT	1.2 ± 0.05	1.6 ± 0.07	1.6 ± 0.06
	Sig1R KO	1.2 ± 0.03	1.3 ± 0.03 *	1.3 ± 0.05 *
Pancreas	WT	0.7 ± 0.07	1.0 ± 0.11	0.9 ± 0.07
	Sig1R KO	0.8 ± 0.06	0.5 ± 0.08 *	0.6 ± 0.05 *
Liver	WT	4.5 ± 0.09	5.2 ± 0.43	5.2 ± 0.33
	Sig1R KO	4.4 ± 0.10	4.8 ± 0.35	4.9 ± 0.35

Data are shown as the mean ± SEM (n = 5–10 mice/group). * p < 0.05 vs. WT mice.