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CCL4 promotes OSCC angiogenesis in vivo. Mice were injected subcutaneously with Matrigel containing 0.2 mL CM from OSCC cells (treated with or without CCL4). On Day 14, Matrigel plugs were excised, photographed, quantified for hemoglobin content (A), then stained with CD31 (B–D). * p < 0.05 compared with controls.
