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Study outline. db/db UNx-ReninAAV mice were treated (q.d.) with vehicle (s.c.), semaglutide (30 nmol/kg, s.c., or combination treatment with semaglutide (30 nmol/kg, s.c.) + lisinopril (30 mg/kg, p.o.) for 11 weeks. Abbreviations: AAV, adeno-associated virus; Acclim., acclimatization; BG, blood glucose; BP, blood pressure; BW, body weight; i.v., intravenous; UNx, uninephrectomy.
