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. 2022 Jul 21;10(7):1759. doi: 10.3390/biomedicines10071759

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effect of fenoterol on calcium wave frequency. (A) Recordings of a spontaneous calcium transient or wave before and after exposure to 3 µM Feno. Impact of Feno on (B) event frequency, (C) rate of rise of the calcium signal, (D) time integral of the calcium signal. p-values were obtained using Wilcoxon’s rank sum test. Statistically significant differences between pairs of bars are indicated with ***: p < 0.001. Circles in (B–D) correspond with the values of individual data points. Number of cells/number of patients is given below bars.