Table 2.
Comparison of the Response to 3 µM Fenoterol and 100 nM Isoproterenol.
| Properties | Fenoterol | Isoproterenol |
|---|---|---|
| CALCIUM SPARKS (cells/patients) | (45/11) | (30/9) |
| Density (events/s/1000 µm2) | 0.52 ± 0.11 | 0.53 ± 0.12 |
| Site density (sites/1000 µm2) | 9.55 ± 1.36 | 11.5 ± 1.1 |
| Sparks/site (events/s) | 0.042 ± 0.005 | 0.039 ± 0.011 |
| Distance to nearest neighbor (µm) | 2.39 ± 0.39 | 3.66 ± 0.64 |
| Amplitude (ΔF/F0) | 1.48 ± 0.21 | 1.23 ± 0.16 |
| Rate of Rise (ΔF/F0/s) | 0.025 ± 0.004 | 0.028 ± 0.003 |
| Tau (ms) | 55.4 ± 3.8 | 43.3 ± 3.6 * |
| FDHM (ms) 1 | 65.7 ± 5.4 | 56.9 ± 2.8 |
| FWHM (µm) 2 | 3.06 ± 0.16 | 2.44 ± 0.19 * |
| Mass (∆F × ms × µm) | 289 ± 43 | 182 ± 27 * |
| CALCIUM WAVES 3 | ||
| Frequency (events/min) | 2.89 ± 0.65 | 1.98 ± 0.94 |
1 Full duration at half maximum. 2 Full width at half maximum. 3 Includes both calcium waves and spontaneous calcium transients. * Statistical significance for differences between Feno and Iso is indicated with * p < 0.05.