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. 2022 Jun 29;10(7):1554. doi: 10.3390/biomedicines10071554

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The illustration of the segmentation of thyroid nodule vascularity into: (A) peripheral and (B) central regions. (C) shows the primary ROI from which the overall vascularity is calculated. The VI for the different segments is calculated by the algorithm as the percentage between the total number of pixels (left) and the number of colour pixels without the grey scale pixels (right) within the segmented areas. The RVI is the ratio of the VIs of peripheral regions to that of central regions.