Skip to main content
. 2022 Jul 7;12(7):891. doi: 10.3390/brainsci12070891

Table 2.

GASS and UKU scales, events, and validation measures (sensitivity, specificity, positive predictive value, negative predictive value, phi correlation coefficient).

Corresponding Items Side-Effect Present Concurrent Validity Measures
GASS UKU GASS Events (%) UKU Events (%) Sens. (%) Spec.
(%)
PPV (%) NPV (%) Phi
(ϕ)
ϕ
Int.
1  Asthenia 69 44 39.3 79.5 71 50.7 0.20 M
2  Sedation 28 25 76 40 79.2 35.7 0.15 W
3  Orthostatic hypotension 27 21 82.3 61.9 89 48.1 0.41 RS
4  Palpitations 41 24 75 91.7 96.6 53.7 0.58 RS
5  Dystonia 34 8 68.5 62.5 95.5 14.7 0.18 W
6  Tremor 41 26 75.7 88.5 94.9 56.1 0.57 RS
7  Akathisia 29 18 79.3 66.7 91.5 41.4 0.39 M
8  Increased salivation 26 3 75.3 66.7 98.6 7.7 0.16 W
9  Hypokinesia 53 24 55.3 79.2 89.4 35.8 0.29 M
10  Hyperkinesia 21 5 78.9 20 94.9 4.8 0.01 N
11  Blurred vision 29 15 74.1 46.7 88.7 24.1 0.16 W
12  Dry mouth 53 42 65.5 78.6 80.9 62.3 0.44 RS
13  Dysuria 22 13 85.1 69.2 94.9 40.9 0.44 RS
14  Nausea/Vomiting 26 15 82.4 73.3 94.6 42.3 0.45 RS
15  Nocturnal enuresis 10 42 98.3 21.4 63.3 90 0.32 M
16  Polyuria/Polydipsia 53 33 58.2 75.8 83 47.2 0.32 M
17  Gynecomastia/Breast pain 9 9 93.4 33.3 93.4 33.3 0.27 M
18  Galactorrhea 2 1 99 100 100 50 0.70 S
19  Sexual dysfunction 30 49 88.2 49 64.3 80 0.41 RS
20  Erectile dysfunction 18 16 91.7 68.8 93.9 61.1 0.58 RS
21  Menstruation changes 4 6 98.9 50 96.9 75 0.59 RS
22  Weight gain 42 33 80.6 87.9 93.1 69 0.65 S

GASS: Glasgow Antipsychotic Side Effect Scale; UKU: Udvalg for Kliniske Undersøgelser side-effects scale; Sens.: sensitivity; Spec.: specificity; PPV: positive predictive value; NPV: negative predictive value; Int.: interpretation (based on Rea & Parker anchor points [30]).