Table 2.
Corresponding Items | Side-Effect Present | Concurrent Validity Measures | |||||||
---|---|---|---|---|---|---|---|---|---|
GASS | UKU | GASS Events (%) | UKU Events (%) | Sens. (%) | Spec. (%) |
PPV (%) | NPV (%) | Phi (ϕ) |
ϕ Int. |
1 | Asthenia | 69 | 44 | 39.3 | 79.5 | 71 | 50.7 | 0.20 | M |
2 | Sedation | 28 | 25 | 76 | 40 | 79.2 | 35.7 | 0.15 | W |
3 | Orthostatic hypotension | 27 | 21 | 82.3 | 61.9 | 89 | 48.1 | 0.41 | RS |
4 | Palpitations | 41 | 24 | 75 | 91.7 | 96.6 | 53.7 | 0.58 | RS |
5 | Dystonia | 34 | 8 | 68.5 | 62.5 | 95.5 | 14.7 | 0.18 | W |
6 | Tremor | 41 | 26 | 75.7 | 88.5 | 94.9 | 56.1 | 0.57 | RS |
7 | Akathisia | 29 | 18 | 79.3 | 66.7 | 91.5 | 41.4 | 0.39 | M |
8 | Increased salivation | 26 | 3 | 75.3 | 66.7 | 98.6 | 7.7 | 0.16 | W |
9 | Hypokinesia | 53 | 24 | 55.3 | 79.2 | 89.4 | 35.8 | 0.29 | M |
10 | Hyperkinesia | 21 | 5 | 78.9 | 20 | 94.9 | 4.8 | 0.01 | N |
11 | Blurred vision | 29 | 15 | 74.1 | 46.7 | 88.7 | 24.1 | 0.16 | W |
12 | Dry mouth | 53 | 42 | 65.5 | 78.6 | 80.9 | 62.3 | 0.44 | RS |
13 | Dysuria | 22 | 13 | 85.1 | 69.2 | 94.9 | 40.9 | 0.44 | RS |
14 | Nausea/Vomiting | 26 | 15 | 82.4 | 73.3 | 94.6 | 42.3 | 0.45 | RS |
15 | Nocturnal enuresis | 10 | 42 | 98.3 | 21.4 | 63.3 | 90 | 0.32 | M |
16 | Polyuria/Polydipsia | 53 | 33 | 58.2 | 75.8 | 83 | 47.2 | 0.32 | M |
17 | Gynecomastia/Breast pain | 9 | 9 | 93.4 | 33.3 | 93.4 | 33.3 | 0.27 | M |
18 | Galactorrhea | 2 | 1 | 99 | 100 | 100 | 50 | 0.70 | S |
19 | Sexual dysfunction | 30 | 49 | 88.2 | 49 | 64.3 | 80 | 0.41 | RS |
20 | Erectile dysfunction | 18 | 16 | 91.7 | 68.8 | 93.9 | 61.1 | 0.58 | RS |
21 | Menstruation changes | 4 | 6 | 98.9 | 50 | 96.9 | 75 | 0.59 | RS |
22 | Weight gain | 42 | 33 | 80.6 | 87.9 | 93.1 | 69 | 0.65 | S |
GASS: Glasgow Antipsychotic Side Effect Scale; UKU: Udvalg for Kliniske Undersøgelser side-effects scale; Sens.: sensitivity; Spec.: specificity; PPV: positive predictive value; NPV: negative predictive value; Int.: interpretation (based on Rea & Parker anchor points [30]).