TABLE 2.
Logistic regression with response or remission as criterion and pre‐treatment score on the zest for life item of MADRS‐S as predictor
|
Non‐Response MADRS‐S decrease <50% N (%) |
Response MADRS‐S decrease ≥50% N (%) |
Adjusted OR (95% CI) |
Non‐Remission MADRS‐S 10–51 N (%) |
Remission MADRS‐S 0–9 N (%) |
Adjusted OR (95% CI) |
||
|---|---|---|---|---|---|---|---|
|
MADRS‐S Zest for life item before |
≥4 | 546 (46.3) | 632 (53.7) | 0.75 (0.61–0.92)** | 858 (72.8) | 320 (27.2) | 0.58 (0.48–0.72)*** |
| <4 | 319 (31.6) | 690 (68.4) | 520 (51.5) | 498 (48.5) | |||
|
MADRS‐S total without zest for life item |
7–19 | 23 (37.7) | 38 (62.3) | 0.87 (0.50–1.53) | 29 (47.5) | 32 (52.5) | 1.39 (0.81–2.40) |
| 20–34 | 582 (39.9) | 875 (60.1) | 888 (60.9) | 569 (39.1) | |||
| 35–60 | 260 (38.9) | 409 (61.1) | 1.35 (1.10–1.66)** | 461 (68.9) | 208 (31.1) | 0.93 (0.75–1.15) | |
| Age | 18–30 | 200 (57.0) | 151 (43.0) | 278 (79.2) | 73 (20.8) | ||
| 31–45 | 205 (46.4) | 237 (53.6) | 1.54 (1.15–2.06)** | 313 (70.8) | 129 (29.2) | 1.54 (1.10–2.16) | |
| 46–60 | 242 (42.5) | 328 (57.5) | 1.75 (1.32–2.31)*** | 381 (66.8) | 189 (33.2) | 1.73 (1.25–2.39)*** | |
| 61–75 | 162 (27.9) | 418 (72.1) | 3.04 (2.25–4.12)*** | 287 (49.5) | 293 (50.5) | 2.82 (2.03–3.92)*** | |
| ≥76 | 56 (23.0) | 188 (77.0) | 3.68 (2.49–5.43)*** | 119 (48.8) | 125 (51.2) | 2.57 (1.75–3.78)*** | |
| Sex | Male | 341 (39.7) | 519 (60.3) | 544 (63.3) | 316 (36.7) | ||
| Female | 524 (39.5) | 803 (60.5) | 1.01 (0.84–1.22) | 834 (62.8) | 493 (37.2) | 1.10 (0.91–1.33) | |
| Electrode placement first treatment | RUL | 819 (39.5) | 1257 (60.5) | 1306 (62.9) | 770 (37.1) | ||
| Other | 46 (41.4) | 65 (58.6) | 1.08 (0.71–1.64) | 72 (64.9) | 39 (35.1) | 1.13 (0.73–1.75) | |
| Electrode placement last treatment | Switch of electrode placement | 87 (46.0) | 102 (54.0) | 135 (71.4) | 54 (28.6) | ||
| Same placement | 778 (38.9) | 1220 (61.1) | 1.55 (1.11–2.15)** | 1243 (62.2) | 755 (37.8) | 1.74 (1.21–2.50)** | |
| Diagnosis | Unipolar depression | 710 (39.1) | 1107 (60.9) | 1117 (61.5) | 700 (38.5) | ||
| Bipolar depression | 155 (41.9) | 215 (58.1) | 0.98 (0.77–1.24) | 261 (70.5) | 109 (29.5) | 0.72 (0.56–0.94)** | |
| Psychotic depression | No | 779 (42.9) | 1035 (57.1) | 1203 (66.3) | 611 (33.7) | ||
| Yes | 86 (23.1) | 287 (76.9) | 2.31 (1.77–3.02)*** | 175 (46.9) | 198 (53.1) | 2.00 (1.58–2.54)*** | |
| Personality disorder diagnosed | No | 678 (36.7) | 1167 (63.3) | 1099 (59.6) | 746 (40.4) | ||
| Yes | 187 (54.7) | 155 (45.3) | 0.58 (0.45–0.75)*** | 279 (81.6) | 63 (18.4) | 0.46 (0.34–0.63)*** | |
| Number of earlier suicide attempts | 0 | 662 (38.4) | 1061 (61.6) | 1051 (61.0) | 672 (39.0) | ||
| 1–2 | 136 (41.0) | 196 (59.0) | 1.16 (0.90–1.50) | 223 (67.2) | 109 (32.8) | 1.06 (0.81–1.39) | |
| 3–107 | 67 (50.8) | 65 (49.2) | 1.10 (0.74–1.64) | 104 (78.8) | 28 (21.2) | 0.91 (0.57–1.46) |
Abbreviations: MADRS‐S, Montgomery Åsberg Depression Rating Scale‐Self Assessment; OR, odds ratio; RUL, right unilateral.
**p < 0.01; ***p < 0.001.