TABLE 2.
A list of 40 detected genes harboring two or more protein truncating variants (PTVs) found in benign tissue samples from 35 patients with familial pancreatic cancer
| Genes | Chromosome | Number of PTVs | Gene Bank accession number |
|---|---|---|---|
| COL4A2,COL4A2‐AS2 | 13 | 3 | NM_001846.3,NM_001267044.1 |
| CRIPAK | 4 | 3 | NM_175918.3 |
| MYO15B | 17 | 3 | NM_001309242.1 |
| SYNE2 | 14 | 3 | NM_182914.2 |
| TYRO3 | 15 | 3 | NM_006293.3 |
| ABCA7 | 19 | 2 | NM_019112.3 |
| ABHD16B | 20 | 2 | NM_080622.3 |
| AGBL3 | 7 | 2 | NM_178563.3 |
| APLF | 2 | 2 | NM_173545.2 |
| ASGR1 | 17 | 2 | NM_001671.4 |
| ATM | 11 | 2 | NM_000051.3 |
| BRCA2 | 13 | 2 | NM_000059.3 |
| CNKSR3 | 6 | 2 | NM_173515.2 |
| CNOT2 | 12 | 2 | NM_014515.5 |
| EPPK1 | 8 | 2 | NM_031308.3 |
| FBRSL1 | 12 | 2 | NM_001142641.1 |
| GPSM3 | 6 | 2 | NM_022107.2 |
| GSX1 | 13 | 2 | NM_145657.2 |
| HABP2 | 10 | 2 | NM_004132.4 |
| HOOK3 | 8 | 2 | NM_032410.3 |
| KIAA0100 | 17 | 2 | NM_014680.3 |
| LOC101928841 | 13 | 2 | NM_001304433.1 |
| NEK8 | 17 | 2 | NM_178170.2 |
| OXER1 | 2 | 2 | NM_148962.4 |
| PABPC1 | 8 | 2 | NM_002568.3 |
| PDE3B | 11 | 2 | NM_000922.3 |
| PIH1D1 | 19 | 2 | NM_017916.2 |
| POLE | 12 | 2 | NM_006231.3 |
| PRKCD | 3 | 2 | NM_006254.3 |
| RICTOR | 5 | 2 | NM_001285439.1 |
| RP1L1 | 8 | 2 | NM_178857.5 |
| RPS6KA4 | 11 | 2 | NM_003942.2 |
| SENP7 | 3 | 2 | NM_020654.4 |
| SPG11 | 15 | 2 | NM_025137.3 |
| SSC5D | 19 | 2 | NM_001144950.1 |
| ST8SIA4 | 5 | 2 | NM_005668.5 |
| STAB1 | 3 | 2 | NM_015136.2 |
| TTC27 | 2 | 2 | NM_017735.4 |
| TTC6 | 14 | 2 | NM_001310135.1 |
| ZNF628 | 19 | 2 | NM_033113.2 |