Table 2.
The roles of exosomal lncRNAs in cancers.
| Cancer type | Exosomal lncRNAs | Functions of exosomal lncRNAs | References |
|---|---|---|---|
| BCa | lncRNA-SNHG1 | Promote trastuzumab chemoresistance | [73] |
| lncRNA UCA1 | Induce drug resistance | [74] | |
| lncRNA AGAP2-AS1 | Induce drug resistance | [75] | |
| lncRNA AFAP1-AS1 | Induce drug resistance | [76] | |
| lncRNA H19 | Induce drug resistance | [77] | |
|
| |||
| CRC | LNCV6_116109, LNCV6_98390, LNCV6_38772, LNCV_108266, LNCV6_84003, and LNCV6_98602 | Upregulated in CRC patients | [78] |
| lncRNA LINC02418 | Diagnosis and prognosis | [79] | |
| lncRNA RPPH1 | Diagnostic marker | [80] | |
| lncRNA CRNDE-h | Diagnosis and prognosis | [81] | |
| GC | LncRNA HOTTIP | Upregulated in serum exosomes from GC patients | [82] |
| HCC | LncRNA-H19 | Promote angiogenesis and adhesion of CD90+Huh7 cells to endothelial cell monolayer | [83] |
| NSCLC | lncRNA MALAT-1 | Promote cell proliferation and migration | [84] |
| RCC | LncRNA-ARSR | Transmit to sensitive cells and disseminate sunitinib resistance | [85] |
BCa, breast cancer; CRC, colorectal cancer; GC, gastric cancer; HCC, hepatocellular carcinoma; NSCLC, non-small-cell lung cancer; RCC, renal cell carcinoma.