TABLE 1.
Characteristic | ALS, n = 143 |
---|---|
Gender, M/F | 87/56 |
Age at venipuncture, years | 64.0 (55.0–72.0) |
Disease duration at venipuncture, months | 9.0 (7.0–12.0) |
Diagnostic delay, months | 7.0 (5.0–10.0) |
ALSFRS‐R | 41.0 (36.0–44.0) |
ΔALSFRS‐R, points/month | 0.9 (0.5–1.5) |
MRC total score | 106.0 (94.8–114.0) |
ΔMRC, points/month | 1.7 (0.7–2.7) |
UMN score | 8.0 (4.0–11.0) |
ECAS ALS‐specific | 71.0 (56.0–84.0) |
ECAS ALS‐nonspecific | 23.0 (18.0–27.0) |
Total ECAS score | 93.0 (76.0–109.0) |
Mean MEP/cMAP at four limbs | 0.2 (0.1–0.3) |
Given are median values and interquartile range.
Abbreviations: ALS, amyotrophic lateral sclerosis; ALSFRS‐R, ALS Functional Rating Scale–Revised; ECAS, Edinburgh Cognitive and Behavioural ALS Screen; F, female; M, male; MEP/cMAP, motor evoked potential/compound muscle action potential; MRC, Medical Research Council Scale; UMN, upper motor neuron; ΔALSFRS‐R, ALSFRS‐R progression rate; ΔMRC, MRC progression rate.