History of psoriasis (PSO), either personal or family history, is an important factor in the diagnosis of psoriatic arthritis (PsA).

We unveiled potential differences in disease patterns, especially axial joints, of patients with or without the history of PSO, either personal or family history.

Patients with existing skin lesion or a past history of PSO is correlated with the higher disease activity, particularly more severe axial involvement.

Customized treatments are needed by taking the skin disease, family history of PSO, and potential axial involvements into consideration.