Table 3.

Study data for flare incidence (per patient per year) over the 12 and 24 months before and after belimumab treatment

Study	After treatment			Before treatment
	N	Mean	SE	N	Mean	SE
Over 12 months
Gatto 2020	262	0.42	0.04	262	1.39	0.07
Iaccarino 2017	38	0.26	0.08a	38	0.78	0.14
Iaccarino 2018	111	0.39	0.05	111	1	0.08
Fixed-effect average		0.39	0.03		1.15	0.05
Random-effect average		0.38	0.04		1.07	0.17
I2	34%			91%
Over 24 months
Gatto 2020	234	0.31	0.03	234	1.02	0.05
Iaccarino 2017	18	0.22	0.08a	18	0.75	0.14
Iaccarino 2018	54	0.265	0.06	54	0.705	0.09
Fixed-effect average		0.30	0.02		0.93	0.04
Random-effect average		0.31	0.01		0.84	0.12
I2	79%			84%

SE standard error

^aEstimated from mean and patient-years of follow-up