Hyaluronic acid-based viscosupplementation therapy has become established as a valid and consolidated therapeutic approach in the management of osteoarthritis and other joint diseases.

Innovative hybrid cooperative complexes of high and low molecular weight hyaluronic acid (HA-HL) and hyaluronic acid plus sodium chondroitin (HA-SC) have been developed to improve the usefulness and the efficacy of intra-articular viscosupplementation in osteoarthritis and other joint diseases.

HA-HL and HA-SC can deliver a high concentration of GAGs to affected joints accompanied by a lack of systemic or local side effects.