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. 2022 Jul 12;9:944180. doi: 10.3389/fcvm.2022.944180

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Copyright © 2022 Ibrahim, Bleichert, Klopf, Kurzreiter, Knöbl, Hayden, Busch, Stiglbauer-Tscholakoff, Eilenberg, Neumayer, Bailey and Brostjan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Ex vivo measurements of maximum aortic diameter compared to ultrasound derived AAA parameters. (A–D) Excised aortas are shown in top panels, while 3D reconstructed aorta volumes are illustrated in bottom panels for the (A) AngII model, (B) ePPE model, (C) ePPE + BAPN model, (D) PPE model. The length of US screened aorta regions (12 mm) is indicated in the respective images of excised aortas by a dashed turquoise line. (E,G) The correlation between maximum aortic diameter as determined by 3D US or measured ex vivo in the (E) AngII model and (G) PPE model were evaluated by Spearman coefficient of correlation. The comparison between ex vivo AAA diameter and 3D US volume is shown in (F) for the AngII model and (H) for the PPE model.