TABLE 1.

Association of endotoxemia (serum lipopolysaccharide activity) with demographic factors and cardiometabolic disorders

Group	Parameter	Beta, P‐value
	Age, years	0.037, 0.003
	Gender	−0.017, 0.173
	Current smoking	−0.011, 0.360
	Number of extracted teeth	0.031, 0.020
	Education, years	−0.024, 0.074
	Fasting time, h	−0.001, 0.954
Cardiometabolic disorder	Diabetes mellitus, coronary heart disease, obesity, or metabolic syndrome	0.178, <0.001
Obesity	Body mass index, kg/m2	0.213, <0.001
	Waist/hip ratio	0.201, <0.001
	Weight, kg	0.182, <0.001
Physical activity	Amount in week, h	−0.029, 0.021
	At work	−0.014, 0.264
	Leisure time	−0.073, <0.001
Diabetes	Plasma glucose, mg/dl	0.056, <0.001
	Prevalent diabetes	0.058, <0.001
Hypertension	Prevalent hypertension (American Heart Association definition)	0.120, <0.001
	Systolic blood pressure, mm Hg	0.096, <0.001
	Diastolic blood pressure, mm Hg	0.127, <0.001
	Pulse, n/min	0.061, <0.001
Metabolic syndrome	Prevalent metabolic syndrome (International Diabetes Federation definition)	0.288, <0.001
	Number of metabolic syndrome components	0.327, <0.001
Cardiovascular diseases	Prevalent cardiovascular diseases	0.030, 0.018
	Prevalent coronary heart disease	0.029, 0.019
	Prevalent acute myocardial infarction	0.034, 0.007
Liver function	Carbohydrate‐deficient transferrin, U/L	0.056, <0.001
	Alcohol consumption, g/week	0.038, 0.002
	gamma‐Glutamyltransferase, U/L	0.145, <0.001
Clinical biochemistry	Creatinine, mg/dl	0.026, 0.040
	Cystatin C, mg/L	0.088, <0.001
	Apolipoprotein‐B, g/L	0.282, <0.001
	Apolipoprotein‐A1, g/L	0.016, 0.207
	High‐density lipoprotein cholesterol, mmol/L	−0.160, <0.001
	Triglycerides, mmol/L	0.570, <0.001
	Cholesterol, mmol/L	0.285, <0.001
Inflammation	C‐reactive protein, mg/L	0.051, <0.001
	Adiponectin, μg/ml	−0.086, <0.001
	Serum amyloid A, mg/L	−0.031, 0.223

All linear models are adjusted for age, gender, and current smoking. N = 6782. Originally described in ¹¹³ , ¹⁹³ Statistically significant values are in bold.