TABLE 4.
Survival analysis outcomes
| Overall survival (months) | P value | C‐index | Recurrence‐free survival (months) | P value | C‐index | |
|---|---|---|---|---|---|---|
| All patients | 53.2 (50.3–56.2) | — | — | 32.0 (25.0–50.0) | — | — |
| Pathologically confirmed MVI | ||||||
| MVI positive | 61.0 (42.0–61.0) | <.001 | 0.715 (0.632–0.798) | 12.0 (9.0–25.0) | <.001 | 0.684 (0.625–0.743) |
| MVI negative | Not reached | 50.0 (39.0–50.0) | ||||
| Optimal model based on the MVI score | ||||||
| Model‐predicted positive (>20 points) | 61.0 (42.0–61.0) | <.001 | 0.700 (0.603–0.797) | 13.0 (8.0–28.0) | <.001 | 0.652 (0.588–0.716) |
| Model‐predicted negative (≤20 points) | Not reached | 42.0 (36.0–50.0) | ||||
| Risk system based on the MVI score | ||||||
| Low risk (≤12 points) | Not reached | <.001 | 0.762 (0.679–0.845) | Not reached | <.001 | 0.708 (0.649–0.767) |
| Medium risk (13–26 points) | Not reached | 42.0 (25.0–44.0) | ||||
| High risk (>26 points) | 36.0 (22.0–61.0) | 7.0 (5.0–12.0) | ||||
Note: Unless stated otherwise, data are presented as median (95% confidence intervals).
Data are mean (95% confidence intervals) because the median time was not reached.
Abbreviation: MVI, microvascular invasion.