FIGURE 2.

Characteristics of PBMCs subtypes in HDV patients. A, HDV specific CD8⁺ T cells presenting with a memory‐like phenotype along with increased expression of the innate‐like receptor NKG2D. B, The NK cell population is mainly composed of CD56^bright cells with low cytotoxic potential and high cytokine production; both the CD56^bright and the CD56^dim subsets are characterised by a low expression of the CD244 and CD48 surface markers. C, Residual MAIT cells in HDV patients show an exhausted phenotype and a downregulation of costimulatory molecules. Shaded icons represent low expression. HDV, hepatitis delta virus; MAIT, mucosal‐associated invariant T; NK, natural killer; PBMC, peripheral blood mononuclear cell