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. 2022 Mar 29;55(7):1742–1755. doi: 10.1111/ejn.15650

TABLE 1.

Correlation between morphine self‐administration behaviour and miRNA expression after 1 or 30D of abstinence with cue relapse test

Cue relapse test Avg infusions, last 3D D10 active LP Avg active LP over 10D Avg infusions over 10D Relapse test
1D 30D 1D 30D 1D 30D 1D 30D 1D 30D
rno‐mir‐24‐1‐5p p‐value 0.425 0.881 0.555 0.640 0.078 0.545 0.460 0.786 0.311 0.337
Pearson r −0.405 −0.059 0.306 −0.181 0.762 0.234 −0.378 −0.106 −0.501 0.363
rno‐mir‐32‐5p p‐value 0.817 0.442 0.534 0.781 * 0.025 0.542 0.999 0.420 0.407 0.827
Pearson r −0.123 0.294 0.322 0.109 * 0.867 0.235 0.001 0.308 −0.420 0.085
rno‐mir‐101b‐3p p‐value 0.248 0.170 0.539 0.133 0.143 0.300 0.231 0.058 0.147 0.703
Pearson r −0.560 −0.500 0.318 −0.541 0.673 −0.389 −0.577 −0.650 −0.668 0.149
rno‐mir‐137‐3p p‐value 0.272 0.125 0.482 0.163 0.142 0.764 0.230 0.052 0.179 0.183
Pearson r −0.537 −0.551 0.361 −0.507 0.674 −0.117 −0.577 −0.663 −0.631 0.488
rno‐mir‐181a‐3p p‐value 0.743 0.264 0.483 0.763 0.057 0.818 0.786 0.314 0.453 0.641
Pearson r −0.173 0.417 0.360 0.118 0.798 0.090 −0.144 0.379 −0.383 −0.181
rno‐mir‐1298‐5p p‐value 0.340 0.097 0.380 0.149 0.163 0.183 0.241 * 0.040 0.152 0.957
Pearson r −0.476 −0.586 0.442 −0.522 0.649 −0.487 −0.566 * ‐0.688 −0.663 0.021

Note: The bold/italics represent statistical significance.

*

Defines statistical significance.