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. 2022 Mar 29;55(7):1742–1755. doi: 10.1111/ejn.15650

TABLE 2.

Correlation between morphine self‐administration behaviour and miRNA expression after 1 or 30D of abstinence and no relapse test

No relapse test Avg infusions, last 3D D10 active LP Avg active LP over 10D Avg infusions over 10D
1D 30D 1D 30D 1D 30D 1D 30D
rno‐mir‐24‐1‐5p p‐value 0.443 0.062 0.259 0.654 0.119 0.755 0.497 0.099
Pearson r 0.207 0.493 0.300 0.126 0.406 −0.088 0.183 0.442
Rno‐mir‐32‐5p p‐value 0.263 0.178 * 0.030 0.822 0.248 0.823 0.589 0.079
Pearson r 0.309 0.368 * 0.561 0.064 0.318 0.063 0.152 0.467
rno‐mir‐101b‐3p p‐value 0.648 0.102 0.807 0.649 0.949 0.810 0.613 0.172
Pearson r −0.124 0.438 0.066 0.128 0.017 −0.068 −0.137 0.372
rno‐mir‐137‐3p p‐value 0.750 * 0.030 0.160 0.521 0.855 0.857 0.844 0.057
Pearson r 0.087 * 0.560 0.369 0.180 0.050 −0.051 −0.053 0.502
rno‐mir‐181a‐3p p‐value 0.838 0.058 0.775 0.517 0.460 0.945 0.842 0.080
Pearson r 0.056 0.500 0.078 0.182 0.199 0.020 0.054 0.465
rno‐mir‐1298‐5p p‐value * 0.005 0.243 0.140 0.897 * 0.014 0.795 * 0.003 0.390
Pearson r * −0.682 0.322 −0.399 0.036 * −0.619 −0.073 * −0.707 0.239

Note: The bold/italics represent statistical significance.

*

Defines statistical significance.