Table 1.
Characteristics of emergency admissions: survivors vs. non-survivors.
| Characteristic | N (%) |
Estimated differences OR (95% CI) |
p | ||
|---|---|---|---|---|---|
|
All admissions (n = 200) |
Survivors (n = 178) |
Non-survivors (n = 22) |
|||
| Male gender | 102 (51) | 90 (50.6) | 12 (54.5) | 1.2 (0.4–3.2) | 0.9 |
| Age#, years | 8.3 (3.1–14.7) | 7.8 (3–8.4) | 12.6 (4–15.3) | 1.1 (0–0.1) | 0.19 |
| #PICU length of stay (days) | 2.8 (1–7) | 2 (1–5.8) | 8.5 (4.3–26.5) | 1.04 (0–0.1) | 0.006 |
| Severe neutropenia† | 62 (31) | 49 (27.5) | 13 (59) | 3.8 (1.4–10.7) | 0.006 |
| Readmittance | 118 (59) | 104 (58.4) | 14 (63.3) | 1.2 (0.5–3.6) | 0.82 |
| MODS present | 36 (18) | 18 (10.1) | 18 (81.8) | 38.3 (11.1–173.1) | <0.001 |
| Diagnoses | |||||
| Leukemia | 76 (38) | 65 (36.5) | 11 (50) | 1.7 (0.6–4.7) | 0.32 |
| Lymphoma | 29 (14.5) | 25 (14) | 4 | 1.4 (0.3–4.6) | 0.53 |
| Brain/spinal cord | 31 (15.5) | 27 (15.2) | 4 | 1.2 (0.3–4.2) | 0.76 |
| Solid | 28 (14) | 28 (15.7) | 0 | 0 (0–1.1) | 0.05 |
| Hematological | 36 (18) | 33 (18.5) | 3 | 0.7 (0.1–2.6) | 0.77 |
| Transplant history | |||||
| Autologous HSCT | 15 (7.5) | 14 (7.9) | 1 | 0.6 (0–4.1) | 1 |
| Allogeneic hSCT | 56 (28) | 45 (25.3) | 11 (50) | 2.9 (1.1–8.1) | 0.022 |
| SOT | 8 (4) | 8 (4.5) | 0 | 0 (0–4.9) | 0.6 |
| None | 121 (60.5) | 111 (62.4) | 10 (45.5) | 0.5 (0.2–1.4) | 0.165 |
| PICU treatment | |||||
| IMV | 69 (34.5) | 49 (27.5) | 20 (90.1) | 25.9 (5.9–235.5) | <0.001 |
| IMV >2 days | 46 (23) | 29 (16.3) | 17 (77.3) | 17.1 (5.5–64.1) | <0.001 |
| CRRT | 18 (9) | 11 (6.2) | 7 (31.8) | 6.8 (0.9–43.3) | 0.03 |
| ECMO | 7 (3.5) | 4 | 3 | 7 (2–23.4) | 0.001 |
| Inotropic support | 43 (21.5) | 28 (15.7) | 15 (68.2) | 11.3 (3.9–35.9) | <0.001 |
| VIS# | 0 (0–0) | 0 (0–0) | 22 (0–43.9) | 1.1 (0.1–0.2) | <0.001 |
#
Median [interquartile range (IQR)]; PICU, pediatric intensive care unit;
†
at admission; MODS, multiple organ dysfunction syndrome; HSCT, hematopoietic stem cell transplantation; SOT, solid organ transplantation; IMV, invasive mechanical ventilation; CRRT, continuous renal replacement therapy; ECMO, extracorporeal membrane oxygenation; VIS, vasoactive ionotropic score; OR, odds ratio; CI, confidence interval. Bold values denote statistically significant.