Table 2.
List of Genomewide Significant SNPs After Correction Using the Benjamini-Hochberg Method With False Discovery Rate of 20% for 3 Retinal Traits: Drusen Area Within a Central 5 mm Circle, Drusen Area Within a Central 3 mm Circle, and Drusen Volume Within a Central 3 mm Circle
| Measure | Model | SNP (GrCh37) | Chromosome | Position | Score P Value | Nearest Gene(s) |
|---|---|---|---|---|---|---|
| Drusen area within a central 5 mm circle | 1 | rs8125299 | 20 | 4860658 | 8.22 × 10−8 | SLC23A2 |
| Drusen area within a central 3 mm circle | 1 | rs79746087 | 19 | 2489650 | 6.85 × 10−8 | GADD45B, GNG7 |
| Drusen volume within a central 3 mm circle | 1 | rs7028791 | 9 | 113240481 | 1.31 × 10−8 | SLC31A1 |
| 1 | rs7850939 | 9 | 113242405 | 2.27 × 10−8 | SLC31A1 | |
| 1 | rs79746087 | 19 | 2489650 | 6.87 × 10−8 | GADD45B, GNG7 | |
| 2 | rs76316680 | 4 | 138280638 | 1.84 × 10−7 | DPP10-AS3, DPP10-AS1 | |
| 2 | rs17759824 | 2 | 114942278 | 3.73 × 10−7 | SLC7A11, LINC00499 |
If SNP is exonic, the gene that it is located in is listed. If SNP is intergenic, the nearest upstream and downstream genes are listed.