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. 2022 Jul 12;12:815955. doi: 10.3389/fonc.2022.815955

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Copyright © 2022 Xu, Kong and Deng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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A 70-year-old man was diagnosed with cholangiocarcinoma. (A) Axial contrast-enhanced CT image shows an intra-osseous focal hyperdense lesion with a clear margin in the 2nd lumbar vertebral body. (B, C) Rho/Z on DECT shows the placement of ROI over an intra-osseous focal hyperdense lesion. Values of ROI: Z = 12.39, Rho = 726.4, DEI = 0.084, rCT = 1193.0 HU. (D) Intra-osseous focal hyperdense lesion showed no increased radionuclide uptake on bone scintigraphs, and it was diagnosed as BI.