TABLE 1.
Demographic and laboratory parameters of the study population
| Characteristics | Control (n = 16) | Alcohol use disorder (n = 62) | p value |
|---|---|---|---|
| Age (years), n = 78 | 40.8 ± 12.3 | 44.4 ± 11.9 | 0.303 |
| Sex (male), n (%), n = 78 | 13 (81.3) | 44 (71.0) | 0.385 |
| BMI (kg/m2), n = 78 | 23.9 ± 3.8 | 24.3 ± 3.8 | 0.676 |
| AST (IU/L), n = 70 | 18.4 ± 5.1 | 67.5 ± 64.7 | <0.001 |
| ALT (IU/L), n = 70 | 11.3 ± 3.6 | 53.3 ± 42.3 | <0.001 |
| GGT (IU/L), n =69 | 23.0 ± 13.0 | 208.5 ± 291.9 | <0.001 |
| ALP (IU/L), n = 68 | 45.8 ± 22.5 | 79.1 ± 33.6 | 0.003 |
| Bilirubin (mg/dL), n = 70 | 0.2 ± 0.2 | 0.6 ± 0.4 | <0.001 |
| Albumin (g/dL), n = 67 | 4.4 ± 0.1 | 4.6 ± 0.4 | 0.009 |
| INR, n = 61 | n/a | 0.98 ± 0.11 | n/a |
| Creatinine (mg/dL), n = 70 | 0.97 ± 0.18 | 0.80 ± 0.14 | 0.030 |
| Platelet count (109/L), n = 61 | n/a | 228.1 ± 79.3 | n/a |
Values presented are mean ± SD. The number of subjects for which data were available is indicated in the first column.
Abbreviations: ALT, alanine aminotransferase; ALP, alkaline phosphatase; AST, aspartate aminotransferase; BMI, body mass index; GGT, gamma‐glutamyltransferase; INR, international normalized ratio; n/a, not applicable.