TABLE 3.
DAVID enrichment analysis results on up‐regulated genes
| Category | Term | p value | Fold Enrichment | FDR |
|---|---|---|---|---|
| UP_KEYWORDS | Mitochondrion | 1.75E‐79 | 2.55 | 4.06E‐77 |
| UP_KEYWORDS | Mitochondrion inner membrane | 1.22E‐38 | 3.35 | 1.13E‐36 |
| KEGG_PATHWAY | hsa00190:Oxidative phosphorylation | 1.06E‐26 | 3.30 | 1.33E‐24 |
| UP_KEYWORDS | Respiratory chain | 1.64E‐20 | 4.75 | 7.61E‐19 |
| KEGG_PATHWAY | hsa04932:Nonalcoholic fatty liver disease | 2.01E‐13 | 2.44 | 6.34E‐12 |
| KEGG_PATHWAY | hsa05012:Parkinson's disease | 1.04E‐19 | 2.86 | 8.73E‐18 |
| KEGG_PATHWAY | hsa05016:Huntington's disease | 6.20E‐17 | 2.43 | 3.91E‐15 |
| KEGG_PATHWAY | hsa05010:Alzheimer's disease | 3.15E‐16 | 2.52 | 1.59E‐14 |
| UP_KEYWORDS | Ribosomal protein | 7.31E‐71 | 5.12 | 1.13E‐68 |
| UP_KEYWORDS | Cell cycle | 8.70E‐13 | 1.74 | 2.12E‐11 |
| UP_KEYWORDS | Cell division | 1.10E‐09 | 1.84 | 1.96E‐08 |
| UP_KEYWORDS | DNA repair | 7.52E‐06 | 1.70 | 7.40E‐05 |
| UP_KEYWORDS | DNA damage | 1.15E‐05 | 1.62 | 1.11E‐04 |
| GOTERM_BP_DIRECT | GO:0042769~DNA damage response, detection of DNA damage | 4.19E‐09 | 3.97 | 8.42E‐07 |
| GOTERM_BP_DIRECT | GO:0006283~transcription‐coupled nucleotide‐excision repair | 5.80E‐07 | 2.63 | 7.77E‐05 |
| KEGG_PATHWAY | hsa03430:Mismatch repair | 1.09E‐03 | 2.87 | 1.31E‐02 |
| GOTERM_BP_DIRECT | GO:0000715~nucleotide‐excision repair, DNA damage recognition | 4.40E‐05 | 3.67 | 4.08E‐03 |
| UP_KEYWORDS | Antioxidant | 2.13E‐05 | 5.09 | 1.93E‐04 |
| GOTERM_BP_DIRECT | GO:0000302~response to reactive oxygen species | 3.91E‐04 | 2.67 | 2.51E‐02 |
| GOTERM_BP_DIRECT | GO:0098869~cellular oxidant detoxification | 2.31E‐05 | 2.41 | 2.32E‐03 |
Abbreviations: DAVID, Database for Annotation, Visualization, and Integrated Discovery; FDR, false discovery rate; GOTERM, Gene Ontology term; KEGG, Kyoto Encyclopedia of Genes and Genomes.