TABLE 4.
DAVID enrichment analysis results on down‐regulated genes
| Category | Term | p value | Fold Enrichment | FDR |
|---|---|---|---|---|
| UP_KEYWORDS | Cell membrane | 1.45E‐39 | 1.60 | 1.68E‐37 |
| GOTERM_CC_DIRECT | GO:0005886~plasma membrane | 2.66E‐39 | 1.48 | 1.80E‐36 |
| UP_KEYWORDS | Cell junction | 7.35E‐14 | 1.82 | 1.99E‐12 |
| UP_KEYWORDS | Immunoglobulin domain | 1.34E‐52 | 3.02 | 6.19E‐50 |
| GOTERM_MF_DIRECT | GO:0003823~antigen binding | 5.12E‐20 | 3.93 | 7.91E‐17 |
| GOTERM_BP_DIRECT | GO:0050776~regulation of immune response | 2.78E‐18 | 2.98 | 4.32E‐15 |
| GOTERM_BP_DIRECT | GO:0006898~receptor‐mediated endocytosis | 3.42E‐15 | 2.73 | 2.78E‐12 |
| GOTERM_BP_DIRECT | GO:0006956~complement activation | 3.60E‐15 | 3.70 | 2.78E‐12 |
| GOTERM_BP_DIRECT | GO:0050853~B‐cell receptor signaling pathway | 3.13E‐14 | 4.43 | 1.88E‐11 |
| GOTERM_MF_DIRECT | GO:0034987~immunoglobulin receptor binding | 8.89E‐10 | 5.29 | 4.20E‐07 |
| GOTERM_MF_DIRECT | GO:0004896~cytokine receptor activity | 3.86E‐06 | 3.61 | 5.96E‐04 |
Abbreviations: DAVID, Database for Annotation, Visualization, and Integrated Discovery; FDR, false discovery rate; GOTERM, Gene Ontology term; KEGG, Kyoto Encyclopedia of Genes and Genomes.