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. 2022 Mar 9;28(10):1526–1540. doi: 10.1177/13524585221076717

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© The Author(s), 2022

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 6. — nMTR recovery metrics in nMTR lesions using a model that included all pre-lesional, new lesion, and post-lesional measurements (FAS^a).

FAS: full analysis set; GM: gray matter; MTR: magnetization transfer ratio; nMTR: normalized magnetization transfer ratio; WM: white matter.

nMTR drop (i.e. nMTR recovery metrics) describes the total decrease in nMTR from pre- to post-nMTR lesion time points.

^aFAS included all randomized patients with assigned treatments who took at least one dose of study medication.