TABLE 4.

Missing data on the pharmacokinetics of cannabinoids in animals, adults and newborns.

Model	Matrix	Missing data
Animals	Plasma, urine, feces, breast milk	• CBD metabolites and THC-COOH glucuronide concentrations
Adults	Plasma	• Cannabinoids concentrations in pregnant women
	Breast milk	• THC, 11-OH-THC, THC-COOH pharmacokinetics profile over 24 h and more • CBD metabolites concentrations • Pharmacokinetics of CBD and its metabolites after CBD only consumption • Effects of the mode of administration on cannabinoid concentration in breast milk
	Urine	• CBD metabolites concentrations
Newborns	Meconium	• CBD metabolites concentrations • Correlation between cannabinoid concentrations and the frequency of consumption • Correlation between cannabinoid concentrations and the last trimester of use during pregnancy
	Infant blood	• Cannabinoid concentrations