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. 2022 Jul 11;12:791332. doi: 10.3389/fonc.2022.791332

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Copyright © 2022 Mao, Yu, Wang, Ma, Zheng, Zhang, Luo, Wang and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Characteristics of m6A methylation in LUAD. (A) The sequence logo showed the top three m6A motifs. (B) The distribution of m6A peaks in normal and tumor tissues. (C, D) Pie charts showing the distribution of differently methylated m6A peaks. (E) Histogram showing the changes in m6A enrichment between normal and tumor samples. (F) Volcano plots show significantly different m6A peaks. (G) The distribution of altered GGAC sequence per mRNA. (H) The distribution of differentially methylated m6A peaks in human chromosomes. Fold change ≥ 2 and P < 0.05.