Table 7.
GC-MS analysis of metabolites in plasma of pups recovered from mothers receiving the control diet or the bLF-supplemented diet. The parameters were determined at postnatal day 17. The metabolites presented in the table are those for which plasma concentrations are significantly different when comparing the control and the bLF-supplemented groups.
| Metabolites Name | m/z | RT (min) | FC (bLF/cont) | Sub.Class |
|---|---|---|---|---|
| L-arginine monohydrochloride | 274.165 | 9.502 | 2.934 *** | Non-essential amino acids and derivatives |
| Ornithine | 186.091 | 10.414 | 2.087 ** | Non-essential amino acids and derivatives |
| 2,4 Pyridinylmethyl amino carbonyl cyclopropanecarboxylic | 391.172 | 24.183 | 2.759 ** | Non-essential amino acids and derivatives |
| Tetracosamethyl-cyclododecasiloxane | 360.175 | 24.391 | 2.187 *** | Non-essential amino acids and derivatives |
| 4-2-4 Dichlorophenyl 2 methyl perazinyl 1-yl benzonitrile | 260.145 | 9.502 | 3.384 *** | Phenyl ethers |
| 1,2 Bis (2 quinolylmethyl) ethylene | 142.094 | 11.047 | 1.898 ** | Thioethers |
| 1,10 Dicarboxylic acid | 391.172 | 23.306 | 2.691 *** | Organic compounds |
| Heptacosane | 139.042 | 20.935 | 2.596 ** | Alkanes |
| Tetradecanoic acid trimethyl ester | 316.126 | 17.608 | 2.13 * | Lipids |
| Alpha-glucose | 211.082 | 20.617 | 1.824 ** | Carbohydrates |
Data represented are means ± SEM (* p < 0.05, ** p < 0.01, and *** p < 0.001; n = 16 pups per group). The control and lactoferrin groups were compared by an unpaired two-tailed Student’s t-test.