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. 2022 Jun 21;14(7):1314. doi: 10.3390/pharmaceutics14071314

Figure 3.

Figure 3

In vitro doxorubicin (DOX) release patterns in IMP301 according to different FUS parameters. (a) The amount of DOX released depended on intensity (at 250 Hz PRF, 10 s/spot, and 2% duty cycle). (b) The amount of DOX released depended on PRF (at 2.8 kW/cm2, 10 s/spot, and 2% duty cycle). (c) The amount of DOX released depended on irradiation time (at 2.8 kW/cm2, 250 Hz PRF, and 2% duty cycle). (d) The amount of DOX released depended on intensity (W) and duty cycle (%) (at 2.8 kW/cm2, 250 Hz PRF, and 10 s/spot).