Table 2.

PD-L1 binding of selected small molecules evaluated by MST compared to SPR and ITC.

Compounds	MST Kd (nM)	SPR Kd (nM)	ITC Kd (nM)
BMSpep-57 *	19 ± 2	20 ± 2	/
BMS-103 *	44 ± 13	16 ± 2	/
BMS-142 *	13.2 ± 1.5	12 ± 2	/
Pyrazolone 11 **	83 ± 12	/	120
Pyrazolone 17 **	1.19 ± 0.4	/	/
Pyrazolone 32 **	19 ± 3	/	/

* Compounds from BMS, as described in [66]. ** Pyrazolone derivatives, recently designed and characterized [72,73].