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. 2022 Jul 14;14(14):2894. doi: 10.3390/nu14142894

Figure 5.

Figure 5

β-sitosterol inhibits Dexa-induced atrophy in C2C12 myotube and mice via FoxO1/3-dependent signaling. (A) Representative images of the Western blot analyses for FoxO1 and FoxO3 in C2C12 myotube. Right panel show quantification of the indicated proteins. Data shown are mean ± S.D. (n = 3 per group). ** p < 0.01 vs. control; # p < 0.05 vs. Dexa. (B) Representative images of the Western blot analyses for FoxO1 and FoxO3 in gastrocnemius muscles. Right panel show quantification of the indicated proteins. Data shown are mean ± S.D. (n = 3 per group). ** p < 0.01 vs. control; # p < 0.05 vs. Dexa. (C) Representative images of the Western blot analyses for FoxO1 and FoxO3 in tibialis anterior muscles. Right panel show quantification of the indicated proteins. Data shown are mean ± S.D. (n = 3 per group). ** p < 0.01; * p < 0.05 vs. control. Dexa—Dexamethasone; S—β-sitosterol; DS—dexa + β-sitosterol.