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Association of HSPG2 mutations with ICI treatment efficacy in NSCLC. (A) Kaplan–Meier survival curves of NSCLC patients with and without HSPG2 mutations. (B) Representation of multivariate Cox regression model of HSPG2 mutations with multiple confounding factors adjusted. (C) ICI response rate exhibition of HSPG2-mutated and wild-type groups. (D) Multivariate logistic regression model of HSPG2 mutations was performed with clinical and genomic variables taken into consideration.
