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. 2022 Jun 29;14(7):1377. doi: 10.3390/pharmaceutics14071377

Table 2.

Chemical structure and approximate half-life values, t1/2, of NONOates at 37 °C and pH 7.4. Adapted from [81].

N-Diazeniumdiolate Chemical Structure t 1/2
PROLI/NO
1-[-2-(-carboxylate)pyrrolidine-1-yl] NONOate
graphic file with name pharmaceutics-14-01377-i005.jpg 2 s
MAHMA/NO
Methylamine hexamethylene
methylamine NONOate
graphic file with name pharmaceutics-14-01377-i006.jpg 1 min
DEA/NO
Diethylamine NONOate
graphic file with name pharmaceutics-14-01377-i007.jpg 2 min
SPER/NO
Spermine NONOate
graphic file with name pharmaceutics-14-01377-i008.jpg 6 min
PAPA/NO
Propylamine propylamine NONOate
graphic file with name pharmaceutics-14-01377-i009.jpg 15 min
DPTA/NO
Dipropylentriamine NONOate
graphic file with name pharmaceutics-14-01377-i010.jpg 3 h