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. 2022 Jul 4;10(7):1350. doi: 10.3390/microorganisms10071350

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(A) Horizontal gene transfer prediction by HGTector within each sub-section of pan-genome. (B) The taxonomic groups that are predicted to share horizontally transferred genes with A. muciniphila. It has been observed that the majority of taxonomic groups reside in the gastrointestinal tract. (C) Genomic Islands as indicated by IslandViewer4. (D) Ka/Ks in the genes belonging to the persistent, cloud, and shell genomes. Genes that belong to the persistent genome showed the least values of Ka/Ks followed by the cloud and shell genomes. (E) Essentiality analysis of the pan-genome. The overlap shows the common essential gene that reveals high similarity with genes from more than one sub-section of the pan-genome. Significance is denoted by: “***” if p value is less than 0.001.