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. 2022 Jul 21;11(14):4233. doi: 10.3390/jcm11144233

Table 2.

Study Population. RSV: respiratory syncytial virus. * Home therapy before hospital admission (hypertonic solution and/or Bronchodilators and/or Cortisone for od).

All
(n = 233)
Bronchiolitis Mild (n = 160) Bronchiolitis Moderate/Severe (n = 73) p Value
Characteristics
Age, days (SD) 109.3 (±86.1) 122.7 (±92.1) 80 (±62.3) 0.001
Sex 0.019
   Female, n° (%) 93 (39.9%) 72 (45%) 21 (28.8%)
   Male, n° (%) 140 (60.1%) 88 (55%) 52 (71.2%)
Prematurity (n = 230)
   Yes, n° (%) 20 (8.7%) 11 (7.0%) 9 (12.3%) 0.182
History of difficulty in feeding (n = 228)
   Yes, n° (%) 151 (66.2%) 92 (59.4%) 59 (80.8%) 0.001
* Home therapy before hospital admission for three days (n = 231)
   Yes, n° (%) 117 (50.6%) 85 (53.8%) 32 (43.8%) 0.159
Rhinorrhea (n = 231)
   Yes, n° (%) 227 (98.3%) 156 (98.7%) 71 (97.3%) 0.425
Crackling noises on physical examination (n = 230)
   Yes, n° (%) 198 (86.1) 134 (84.8%) 64 (88.9%) 0.407
Wheezing (n = 230)
   Yes, n° (%) 154 (67%) 107 (67.7%) 47 (65.3%) 0.715
Fever (n = 231)
   Yes, n° (%) 83 (35.9%) 52 (32.9%) 31 (42.5%) 0.159
Intercostal retractions (n = 231)
   Yes, n° (%) 164 (71%) 96 (60.8%) 68 (93.2%) 0.001
Increased Respiratory Rate (n = 230)
   Under 50 breath/min, n° (%) 75 (32.6%) 35 (22.3%) 40 (54.8%) 0.001
   Between 51–60 breath/min, n° (%) 106 (46.1%) 95 (60.5%) 11 (15.1%)
   Above 61, breath/min 49 (21.3%) 27 (17.2%) 22 (30.1%)
Oxygen saturation (n = 229)
   Under 92% in aa, n° (%) 39 (17%) 10 (6.4%) 29 (39.7%) 0.001
   Between 93–95% in aa, n° (%) 45 (19.7%) 17 (10.9%) 28 (38.4%)
   Above 95% in aa, n° (%) 145 (63.3%) 129 (82.7%) 16 (21.9%)
RSV (n = 216)
   Positive, n° (%) 126 (58.3%) 73 (51.0%) 53 (72.6%) 0.002
Chest X-ray (n = 228)
   No, n° (%) 160 (70.2%)
   Yes, n° (%) 68 (29.8%) 29 (18.7%) 39 (53.4%) 0.001
Hospitalization
   Yes, n° (%) 192 (82.4%) 119 (74.4%) 73 (100.0%) 0.001
HFNC (n = 225)
   Yes, n° (%) 50 (22.2%) 16 (10.5%) 34 (47.2%) <0.001
nCPAP (n = 225)
   Yes, n° (%) 5 (2.2%) 0 (0%) 5 (6.9%) 0.001