Fig. 5.

ISPIP is robust to poor performance of input classifier: On the left, the structure of 1CP2.A) is shown. In the middle, the interface prediction of the 3 input classifiers is displayed. PredUs 2.0 has an especially poor prediction relative to the other 2 input classifiers. On the right, the ISPIP has a robust consensus prediction with 10 TP out of the 13 annotated residues, despite the poor performance of the PredUs 2.0 input classifier